Jorge Carneiro is a Principal Investigator at the Laboratório Associado ITQB and at Instituto Gulbenkian de Ciência (IGC), where he heads the Quantitative Organism Biology lab. He is the Director of the PhD Program in Computational Biology, promoted by FCG, FCT and Siemens SA.
Jorge got a degree in Biochemistry from the University of Porto, Portugal, in 1991. He prepared is PhD at the Pasteur Institute in Paris, where he developed immune network models incorporating B and T lymphocytes with John Stewart. He got is PhD in 1997 from the University of Porto. After a short postdoc at the University of Utrecht, with Rob de Boer, he became an independent researcher at IGC.
Jorge's lab was at the forefront of theoretical and quantitative studies on the dynamics of regulatory T cells, responsible for the prevention of autoimmune pathologies in healthy individuals. Together with his collaborators, he predicted the mechanism of action and repertoire selection of these cells, embodied in the Crossregulation Model. His vision of the way the immune system tolerates the organism's tissues and rejects extraneous or pathogen-infected tissues was successfully implemented as spam detection algorithms.
More recently, Jorge gained interest on modelling the form and morphodynamics of cells and tissues during embryo development, and on the quantitative imaging techniques necessary to assess these models.
Jorge is active in the scientific community. He often organises workshops and courses on scientific topics such as mathematical and computational biology, immunology and imaging, as well as topics that are relevant for (young) scientists such as career development and entrepreneurship. Between 1998 and 2004, he was a member of direction of the Portuguese Society of Immunology, acting as Secretary General and Vice-President in the first and second triennia, respectively. He participated in the planning of, fund raised for, and organisation of the PhD Program in Computational Biology, eventually becaming its Director. This program was launched in 2005, being promoted by FCG, FCT and Siemens SA, and also sponsored by FCCN and Fundação PT. Its objectives were to train a limited number of PhDs in mathematical and computational biology at an internationally competitive level and to identify the future field leaders.