Quantitative Organism Biology

Gene expression variability and collective behavior of cell populations

Lectures in the Systems Biology Course
Doctoral Programme in Experimental Biology and Biomedicine, University of Coimbra
December 2nd, 2009

Lecturers

Jorge Carneiro Bio
Instituto Gulbenkian de Ciencia, Oeiras, Portugal

Lectures

09h30-10h10 Noise in Biochemical Processes: Basic concepts and implications

10h10-10h50 Noise in Biochemical Processes: Experimental Observations

10h50-11h10 Break

11h10-12h00 Structure and function of the lognormal distribution of protein abundance per cell

12h00-14h00 Lunch break

14h00-15h00 The double life of a gene locus: Chromatin remodeling and transcription activation dynamics.

15h00-15h20 Break

15h20-16h00 Moments to Cherish: kinetic model identification based on the distributions of biochemical activities in cell populations.

Bibliography